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Tumor mitochondria vaccine for the treatment of cancer
University of Pennsylvania
Vaccine
Oncology
Hit To Lead or Lead Optimization
Researchers at the Ohio State University, led by Dr. Chenglong Li, have designed novel, non-peptidomimetic molecules for use as anti-cancer inhibitors of STAT3, a protein involved in gene expression and associated with various cancers. The molecules were developed using Fragment-based Drug Design (FBDD) and tested for half maximal inhibitory concentration (IC50).
US 2017-0216419 A1