158 |
Max-Planck Innovation |
Oncology |
Small molecule |
Overcoming Disease Persistence in Myeloproliferative Neoplasms (MPN) through Combinatorial Inhibitor Treatment
|
157 |
SRI International |
Oncology |
Peptide |
An Optimized Peptide for Targeting of Epithelial Derived Tumors
|
156 |
Yale University |
Oncology |
Small molecule |
Novel Small Molecule Inhibitor for Treatment of PARP Inhibitor-resistant Ovarian Cancer
|
155 |
Yale University |
Oncology |
Small molecule |
Treatment of KRAS-Variant Cancers with Serotonin Transporter Inhibitors
|
154 |
Wisconsin Alumni Research Foundation |
Fibrosis |
Peptide |
Compositions and Methods for the Inhibition of Fibrosis
|
153 |
Wisconsin Alumni Research Foundation |
Genetic disorders |
Gene therapy |
Gene Correction of Pompe Disease and Other Autosomal Recessive Disorders via CRISPR and other RNA-Guided Nucleases
|
152 |
Wisconsin Alumni Research Foundation |
Oncology |
Cell therapy |
Nonviral Generation of Genome-Edited CAR T Cells
|
151 |
Wisconsin Alumni Research Foundation |
Inflammatory disease |
Protein |
Method to Inhibit Neutrophil Recruitment to Damaged Tissue Using Myeloid-Derived Growth Factor
|
150 |
University of Pennsylvania |
Musculoskeletal disease |
Nucleotide |
Site-Blocking Oligos (SBO) Upregulate Utrophin for Treatment of Duchenne Muscular Dystrophy (DMD)
|
149 |
University of Pennsylvania |
Inflammatory disease |
Nanoparticle |
Novel Nanoparticle Composition Targeting Marginated Leukocytes
|
148 |
University of Pennsylvania |
Oncology |
Cell therapy |
Adoptive T Cell Therapy for Cancer using Mutant KRAS-specific T Cell Receptors for T Cell Engineering
|
147 |
University of Florida |
Oncology |
Small molecule |
Anticancer Agents for Triple-Negative Breast Cancers
|
146 |
University of Florida |
CNS disease |
Nanoparticle |
Antigen-Specific Tolerizing Treatment for Multiple Sclerosis
|
145 |
University of Florida |
Oncology |
Gene therapy |
AAV Vectors for Direct Delivery of shRNA into Islet Cells to Treat Pancreatic Cancer
|
144 |
University of Florida |
Oncology |
Antibody |
Hyal2/Hyal1-Expressing Myeloid Cells as a Target for Cancer Immunotherapy
|
143 |
University of Florida |
Oncology |
Small molecule |
Small Molecule Inhibitors Against Cancer-Associated Protein
|
142 |
University of Colorado |
Oncology |
Small molecule |
Novel Inhibitors of PARP1/2
|
141 |
University of Chicago |
Immunology |
Peptide |
FOXP3 Stapled Peptides to Deactivate Regulatory T Cells
|
140 |
University of Central Florida |
Genitourinary disease |
Small molecule |
Spermine Prodrugs for Treating Low Spermine Disorders
|
139 |
University of California - Los Angeles |
Inflammatory disease |
Nanoparticle |
Liver-Targeting Tolerogenic Nanoparticles
|