9
GDF9_Menopausal symptoms
Monash University
Protein
Obstetrics / Gynecology
Hit To Lead or Lead Optimization
Oocyte quality is the key rate limiting factor in female fertility. An important practical reason to improve our understanding of the determinants of oocyte quality is to enhance the clinical implementation of oocyte in vitro maturation (IVM). An engineered form of the human oocyte-derived growth factor GDF9, which potently stimulates granulosa cell signaling and function. Our ‘Super-GDF9’ has great potential to promote oocyte maturation and advance the clinical implementation of the assisted reproductive technique, IVM.